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賀洪娟

發(fā)布者:張寧發(fā)布時(shí)間:2021-10-09瀏覽次數:1269

聯(lián)系方式

郵箱hehongjuan0727@163.com   

 

個(gè)人簡(jiǎn)介

2000-2004年:西南師范大學(xué)理學(xué)學(xué)士

2004-2009山東大學(xué)生化與分子生物學(xué)博士

2009-2016哈爾濱工業(yè)大學(xué)生命科學(xué)與技術(shù)學(xué)院講師

2017-至  今:哈爾濱工業(yè)大學(xué)生命科學(xué)與技術(shù)學(xué)院副教授

 

Personal Profile

2000-2004  Southwest Normal University, Bachelor of Science

2004-2009  Shandong University, PhD of Biochemistry and molecular Biology

2009-2016  Harbin Institute of Technology, School of Life Science and Technology Lecturer

2017-now  Harbin Institute of Technology, School of Life Science and Technology Assistant Professor

 

研究方向領(lǐng)域

表觀(guān)遺傳學(xué)

Epigenetics

 

研究內容

主要研究組蛋白去甲基化酶在胚胎發(fā)育和腫瘤發(fā)育過(guò)程中的作用機制

 

Research Interests

Mainly research the mechanism of histone demethylase in embryonic development and tumor development

 

研究成果

1. Shuang Cui , Qiong Wu*, Ming Liu, Mu Su, ShiYou Liu, Lan Shao, Xiao Han and Hongjuan He*. EphA2 super-enhancer promotes tumor progression by recruiting FOSL2 and TCF7L2 to activate the target gene EphA2.Cell Death and Disease . 2021 Mar 12;12(3):264.

2. Li H*, He H*, Wang Z, Cai J, Sun B, Wu Q, Zhang Y, Zhou G, Yang L: Rice protein suppresses ROS generation and stimulates antioxidant gene expression via Nrf2 activation in adult rats. Gene 2016, 585(2):256-264.

3. Guo J, He H, Liu H, Liu Q, Zhang L, Liu B, Sugimoto K, Wu Q: Aquaporin-1, a New Maternally Expressed Gene, Regulates Placental Development in the Mouse. Biology of reproduction 2016, 95(2):40.

4. Guo J, He H, Liu Q, Zhang F, Lv J, Zeng T, Gu N, Wu Q: Identification and Epigenetic Analysis of a Maternally Imprinted Gene Qpct. Mol Cells 2015, 38(10):859-865.

5. Zeng TB, He HJ, Han ZB, Zhang FW, Huang ZJ, Liu Q, Cui W, Wu Q: DNA methylation dynamics of a maternally methylated DMR in the mouse Dlk1-Dio3 domain. FEBS letters 2014, 588(24):4665-4671.

 

開(kāi)設的課程

發(fā)育生物學(xué)

Developmental Biology

進(jìn)化生物學(xué)

Evolutionary Biology

發(fā)育生物學(xué)實(shí)驗

Developmental Biology Experiments 

 

教師個(gè)人主頁(yè)鏈接

http://homepage.hit.edu.cn/hehongjuan