聯(lián)系方式   

郵箱：liucp74@hotmail.com

個(gè)人簡(jiǎn)介

1993-1997年：吉林大學(xué)理學(xué)學(xué)士（Jilin University, B.Sc.）

1997-2000年：吉林大學(xué)理學(xué)碩士（Jilin University, M.Sc）

2000-2004年：中科院生物物理研究所理學(xué)博士（Institute of Biophysics, CAS, Ph.D.）

2005-2007年：賓西法尼亞大學(xué)理學(xué)博士后（University of Pennsylvania, Postdoc）

2008-2021年：哈爾濱工業(yè)大學(xué)理學(xué)副教授（Harbin Institute of Technology, Assoc. Prof.）

研究方向和領(lǐng)域

分子伴侶

Chaperone

酶學(xué)

Enzymology

研究?jì)热?/span>

分子伴侶構效關(guān)系以及對蛋白內穩態(tài)的影響作用機制；蛋白修飾酶生理功能及其抑制劑開(kāi)發(fā)

The relationship of structure and function of chaperones and their roles in proteostasis maintenance;the physiological roles of protein modifiers and their inhibitor

研究成果

1.^**Zhongya Sun#; Hao Zhang#; Yuanyuan Zhang#; Liping Liao#; Wen Zhou#; Fengcai Zhang; Fulin Lian; Jing Huang; Pan Xu; Rukang Zhang; Wenchao Lu; Mingrui Zhu; Hongru Tao; Feng Yang; Hong Ding; Shijie Chen; Liyan Yue; Bing Zhou; Naixia Zhang; Minjia Tan; Hualiang Jiang; Kaixian Chen; Bo Liu*; Chuanpeng Liu*; Yongjun Dang*; Cheng Luo*; Covalent inhibitors allosterically block the activation of Rho family proteins and suppress cancer cell invasion, Advanced Science,2020, 7(14): 2000098

2.Feng-cai Zhang#; Zhong-ya Sun#; Li-ping Liao; Yu Zuo; Dan Zhang; Jun; Wang; Yan-tao Chen; Sen-hao Xiao; Hao Jiang; Tian Lu; Pan Xu; Li-yan Yue;  Dao-hai Du; Hao Zhang; Chuan-peng Liu*; Cheng Luo*; Discovery of novel CBP. bromodomain inhibitors through TR-FRET-based high-throughput screening, acta pharmacologica sinica, 2020, 41(2): 286-292.

3.^**Dongjie Fan, Shunan Cao, Qiming Zhou, You Zhang, Lei Yue, Chang Han, Bo Yang, Yu Wang, Zhuo Ma, Lingxiang Zhu, Chuanpeng Liu;Exploring the roles of substrate-binding surface of chaperone site in the chaperone activity of trigger factor;The FASEB Journal; 2018, 32(12): 6655-6665

4.Dongjie Fan, Lushan Liu, Lingxiang Zhu, Fang Peng, Qiming Zhou*, Chuanpeng Liu*. (2017) Global Analysis of the Impact of Deleting Trigger Factor on the Transcriptome Profile of Escherichia coli，J.Cell. Biochem. 118(1): 141-153

5.Dongjie Fan, Chuanpeng Liu*, Lushan Liu, Lingxiang Zhu, Fang Peng, Qiming Zhou*. (2016) Large-scale gene expression profiling reveals physiological response to deletion of chaperone dnaKJ in Escherichia coli. Microbiol. Res. 186-187: 27-36

開(kāi)設的課程

分子生物學(xué)

Molecular Biology

生物大分子結構與功能

Structure and Function of Biomacromolecule

分子生物學(xué)進(jìn)展

Progress in Molecular Biology

教師個(gè)人主頁(yè)鏈接

http://homepage.hit.edu.cn/liuchuanpeng