聯(lián)系方式
郵箱:lrjuan@hit.edu.cn
個(gè)人簡(jiǎn)介
教育經(jīng)歷:
2003.9-2007.7 哈爾濱工業(yè)大學(xué) 計算機科學(xué)與技術(shù)專(zhuān)業(yè) 本科
2007.9-2009.7 哈爾濱工業(yè)大學(xué) 計算機科學(xué)與技術(shù)專(zhuān)業(yè) 碩士
2009.9-2015.3 哈爾濱工業(yè)大學(xué) 計算機科學(xué)與技術(shù)專(zhuān)業(yè) 博士
工作經(jīng)歷:
2015.5-2020.12 哈爾濱工業(yè)大學(xué)生命科學(xué)與技術(shù)學(xué)院 講師
2020.12-至今 哈爾濱工業(yè)大學(xué)生命科學(xué)與技術(shù)學(xué)院 副教授
Personal Profile
EDUCATION:
B.Eng.Harbin Institute of Technology, Harbin, China, Computer Science and Technology, 2003-2007
M.Eng.Harbin Institute of Technology, Harbin, China, Computer Science and Technology, 2007-2009
Ph.D. Harbin Institute of Technology, Harbin, China, Computer Science and Technology, 2009-2015
ACADEMIC APPOINTMENTS:
Lecturer, Harbin Institute of Technology, Harbin, China, Biomedical Engineering, 2015-2020
Associate Professor, Harbin Institute of Technology, Harbin, China, Biomedical Engineering, 2020-present
研究方向和領(lǐng)域
生物信息學(xué)
Bioinformatics
研究?jì)热?/span>
主要研究方向為基因組大數據分析方法與軟件,包括三方面內容:
1. 基因組學(xué)機器學(xué)習,研究機器學(xué)習算法在基因組學(xué)問(wèn)題上的應用與改進(jìn);
2. 基因組注釋與可視化,研究對容量龐大、格式多樣、關(guān)系復雜的基因組大數據進(jìn)行注釋及可視化方法與軟件;
3. 多組學(xué)數據分析,運用統計、計算方法,分析多組學(xué)數據、解決生物學(xué)問(wèn)題。
Research Interests
The major research area is methods and software of genome bigdata analysis, including 3 topics:
1. Machine learning in genomics: Improvement and application of machine learning algorithm for genomics.
2. Genome annotation and visualization: Annotation and visualization methods/software for genome bigdata with mass volume, various formats and complex relationship.
3. Multi-omics data analysis, Analyzing multi-omics data by computational and statistical methods, solving biological problem.
研究成果
代表性論文
1. Juan, L.*, Wang, Y., Jiang, J., Yang, Q.,Wang, G., and Wang, Y.* (2020). Evaluating Individual Genome Similarity with a Topic Model. Bioinformatics.(SCI檢索)
2. Juan, L.*, Wang, Y., Jiang, J., Yang, Q.,Jiang, Q., and Wang, Y.* (2020). PGsim: A Comprehensive and Highly Customizable Personal Genome Simulator. Front Bioeng Biotechnol 8, 28.(SCI檢索)
3. Juan, L., Liu, Y., Wang, Y., Teng, M.,Zang, T., and Wang, Y. (2015). Family genome browser: visualizing genomes with pedigree information. Bioinformatics 31, 2262-2268. (SCI檢索)
4. Juan, L., Teng, M., Zang, T., Hao, Y.,Wang, Z., Yan, C., Liu, Y., Li, J., Zhang, T., and Wang, Y. (2014). The personal genome browser: visualizing functions of genetic variants. Nucleic Acids Res 42, W192-197. (SCI檢索)
5. Juan, L., Wang, G., Radovich, M.,Schneider, B.P., Clare, S.E., Wang, Y., and Liu, Y. (2013). Potential roles of microRNAs in regulating long intergenic noncoding RNAs. BMC Medical Genomics 6 Suppl 1,S7. (SCI檢索)
獲獎
2019年度黑龍江省科學(xué)技術(shù)一等獎(排名4)
開(kāi)設的課程
生物信息學(xué)
Bioinformatics
生物數據庫及軟件應用基礎
Foundation of Biological Database and Software
基因組信息學(xué)
Genome Informatics